How the music boosts protein expression in bacteria or eukaryotic cells?

Not all ideas that seem strange are crazy. Many of them are investigated and scientifically proved to be true or possible. Everybody knows that feeling good makes us healthier, more active, and more productive. We’d gladly lock us in a nice circle of feeling happy and getting fit, feeling better and therefore healthier again…

After coming across recent publications in scientific news magazines saying that feeling good helps the mouse body to fight infections, we have asked us a practical question that could be bothering creative microbiologists and biotechnologists:  if the music or other pleasant sounds could have some influence on protein expression efficiency and bio production results.

We hope scientists will find a way to make bacteria or yeast cells feeling so good that their fermentation process boosts to deliver enormous amounts of active target protein.  Good luck with that! Here is a tool which will help you in your experiments and will lead to great results:

Polymer-release system Feed Plate® for cultivation of bacteria, yeast and fungi, and for an easy, rapid and reliable individualized optimization of protein expression.

And below is the inspiring study about happy mice.

Recent article published by a group of scientists from Technion–Israel Institute of Technology in Haifa in Nature Medicine suggests that the immune system of mice can be activated by making the animals feeling good.

The study “Activation of the reward system boosts innate and adaptive immunity” was based on the evidence that the positive expectations mediated by human brain’s reward system contribute to the placebo effect in clinical studies. The aim of the study was to investigate if and how this positive reward system changes the physiology of the body and affects immune response.

The researchers have found out that the mice immune response to bacterial Escherichia coli  infection is boosted in accordance to the activation of the VTA, the ventral tegmental area in the brain, which is considered as being a key component of the reward chain.

Mice with activated nerve cells in the VTA area had much less E. coli bacteria detectable in their bodies compared to control mice without the artificial activation of nerve cells. Mice monocytes and macrophages became significantly more active against the pathogen bacteria after the nerve cell activation.
Scientists have concluded that the enhanced activity of monocytes and macrophages in mice has been at least partially mediated by sympathetic nervous system.

Appropriate clinical studies in humans may explain how the positive thinking and feeling happy could heal us.

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