Protein-specific purification? Easier than you think!

You need more from protein purification than the abilities of commercial resins offer? Standard affinity matrices are limited to recognizing generic tags, whereas protein-specific resins specifically recognize particular proteins or even proteins in a defined conformation.

Chromatography specialists know that the use of such customized resins enables new experimental applications and makes a huge difference in results. Nevertheless opportunities are frequently not explored because of a spread opinion that resin customization is time consuming, expensive and too complicated.

Cube Biotech experts have good news; this myth can be destroyed. Protein resin customization is easier, faster and more economical than you think. You have always two alternative choices:

  • Buy activated beads and make custom resin on your own. It is a perfect way to increase your experiments’ flexibility at lower costs. With a broad choice of activated agaroses and magbeads, you can couple almost every biomolecule to the matrix of your choice with Cube Biotech easy-to-follow protocols and technical support for an easy start.

  • Use customization service provided by experts. Cube Biotech specialists advise you on the most suitable coupling strategy, develop and produce the best performing matrix in the quantities needed—from a few milliliters to bulk volumes.

The possibilities of protein-specific customized matrices are endless; explore them:

  • Purify proteins without an affinity tag
  • Select only proteins in native, active state
  • Purify proteins in a particular conformation
  • Examine protein-agonist interaction
  • Avoid alteration to the target protein due to sub-optimal elution conditions
  • Increased protein homogeneity for crystallization setups

Build your confidence in the best partner for customization needs; start your experience today with best in class standard IMAC resins from Cube Biotech. Free samples available at flash4science for USA, UK and German scientists this week:

Image  by Pierre Tourigny  / CC BY 2.0

Write a comment

Please enter the numbers in the following text field.

The fields marked with * are required.