Protein-specific purification? Easier than you think!
You need more from protein purification than the abilities of commercial resins offer? Standard affinity matrices are limited to recognizing generic tags, whereas protein-specific resins specifically recognize particular proteins or even proteins in a defined conformation.
Chromatography specialists know that the use of such customized resins enables new experimental applications and makes a huge difference in results. Nevertheless opportunities are frequently not explored because of a spread opinion that resin customization is time consuming, expensive and too complicated.
Cube Biotech experts have good news; this myth can be destroyed. Protein resin customization is easier, faster and more economical than you think. You have always two alternative choices:
Buy activated beads and make custom resin on your own. It is a perfect way to increase your experiments’ flexibility at lower costs. With a broad choice of activated agaroses and magbeads, you can couple almost every biomolecule to the matrix of your choice with Cube Biotech easy-to-follow protocols and technical support for an easy start.
Use customization service provided by experts. Cube Biotech specialists advise you on the most suitable coupling strategy, develop and produce the best performing matrix in the quantities needed—from a few milliliters to bulk volumes.
The possibilities of protein-specific customized matrices are endless; explore them:
- Purify proteins without an affinity tag
- Select only proteins in native, active state
- Purify proteins in a particular conformation
- Examine protein-agonist interaction
- Avoid alteration to the target protein due to sub-optimal elution conditions
- Increased protein homogeneity for crystallization setups
Build your confidence in the best partner for customization needs; start your experience today with best in class standard IMAC resins from Cube Biotech. Free samples available at flash4science for USA, UK and German scientists this week: